Pregnancy Labs & Screening
First Trimester (weeks 1-12)
A CBC counts the numbers of different types of cells that make up your blood. It can reveal if you have a certain type of anemia, infection, and/or a problem with blood clotting.
Blood Type/Rh Factor
A blood type test can show if you have the Rh factor. Most people have the Rh factor-they are Rh positive. Others do not have the Rh factor- they are Rh negative. When the Rh is negative you will receive an injection of Rhogam around 28 week's gestation.
An antibody screen detects unusual antibodies which could damage the babyâ€™s red blood cells. These may have arisen during a prior pregnancy or from a blood transfusion.
The rubella titer detects whether you have immunity to rubella from a past infection from German Measles or from prior vaccination. If you have not had the vaccine, you should get it after delivery. You should not be vaccinated against rubella during pregnancy.
A syphilis test will be done at your first prenatal exam and during the third trimester of pregnancy. This is a state required test.
This is a test to detect hepatitis B infection, pregnant women who are infected can pass the virus to their baby.
This is a Commonwealth of Virginia mandated test that detects the Human Immune Deficiency virus, which causes acquired immunodeficiency syndrome (AIDS). Pregnant women who are infected with HIV can be given medications and take other steps that can greatly reduce the risk of passing the virus to their baby. If a pregnant woman declines ante partum HIV testing her newborn will be required to be tested after delivery.
A blood test used to determine if you are producing normal hemoglobin or suffering from a disease causing the production of abnormal hemoglobin including sickle cell anemia or thalassemias.
GC/C is a urine or cervical culture that tests for gonorrhea and Chlamydia, both of which can cause complications for you and your baby. If you test positive for either of these infections, you will be treated during pregnancy and retested to ensure the treatment has worked.
A urine culture tests your urine for bacteria, which can be a sign of an infection. This will be done at your first visit and as needed throughout your pregnancy. A positive culture can put you at risk for a serious kidney infection or preterm delivery.
A urine sample will be tested at each prenatal visit to detect any signs of health problems, particularly urinary tract infections, diabetes, and/or preeclampsia.
First Trimester Screen (optional)
Performed between 11 weeks ,4 days and 13 weeks, 6 days gestation, the First Trimester Screen combines data from a finger stick blood test and a Nuchal Translucency (an ultrasound examination that measures the fluid accumulation behind the fetusâ€™ neck, assess the presence of the nasal bone, and assess blood flow in the heart) to screen and determine your risk for having a baby with Down syndrome, trisomy 18, trisomy 13, or other birth defects. This is performed by a physician in our office. You should plan to stay for up to 2-3 hours. There may be times we have to refer you to another facility for the test. You will then be given the option of scheduling at Martha Jefferson or UVA.
InformaSeq is a blood test done with or without a Nuchal Translucency as early as 10 weeks to assess your risk for having a baby with Down syndrome, trisomy 18, trisomy 13.
Cystic Fibrosis (CF) Carrier Screening (optional)
CF Carrier testing can be performed by taking cells from a blood sample or from cells that are gently scraped from inside the mouth to determine if you are a carrier of the CF mutation gene.
Second Trimester (weeks 13-28)
Alpha fetoprotein (AFP) (optional)
This is a time sensitive blood test only performed between 16-18 weeks that will detect 85% of open neural tube defects or spina bifida. New technologies are available for treatment if early diagnosis is made.
A diagnostic abdominal ultrasound performed between 20 to 24 weeks to evaluate your baby's organs, amniotic fluid, and growth to ensure your baby is properly developing. The results of this ultrasound may influence further management of your pregnancy. A transvaginal ultrasound is also performed at this time to measure the length of your cervix (this can help identify women at more risk of preterm delivery). You may have limit of 2 visitors present for this ultrasound.
A one hour glucose screening test is done at 24 to 28 weeks to determine if you are at risk for developing gestational diabetes. Based on your test results, your provider may suggest a glucose tolerance test.
3-Hour Glucose tolerance test
This test is done to diagnose gestational diabetes. Specific instructions will be provided if testing is required.
If you are Rh negative an indirect coombsâ€™ test will be done at the time of your one hour glucose testing. An indirect coombs' test determines whether there are antibodies to the Rh factor in your blood. A normal (negative) result indicates the fetus is not presently in danger from problems relating to Rh incompatibility. An abnormal (positive) result indicates you have developed antibodies to the fetal RBCs and you are sensitized.
If you are Rh negative you will receive a Rhogam injection around 28 weeks gestation to help prevent future problems with Rh factor. You must have your indirect coombs lab drawn prior to receiving your Rhogam injection.
Repeat CBC or H&H
A repeat CBC or H&H (provider specific) is repeated at the time of your one hour glucose.
Third Trimester (weeks 29-40)
Repeat RPR/VDRL & HIV
Recommended by ACOG and CDC. This may be performed with glucose screen labs.
Group B Strep is a bacteria about 1 in 6 women carry and if not treated during labor can cause pneumonia or serious illness in the newborn. A culture swab is taken from the vaginal/rectal area between 35-37 weeks gestation.
This test may be performed during the latter part of pregnancy to monitor your babyâ€™s health. A fetal monitor is placed around your belly to measure the baby's heart rate in response to its own movements.
Biophysical profile (BPP)
A BPP is sometimes ordered by your provider in the third trimester to monitor the overall health of your baby. It involves an ultrasound exam along with a nonstress test (NST). The BPP examines the baby's breathing, movement, muscle tone, heart rate, and the amount of amniotic fluid.